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At CPhI in Frankfurt, Omya will showcase its Omyapharm® multifunctional excipient platform based on functionalised calcium carbonate, a highly structured mineral. Omyapharm is suitable for numerous applications, including solid oral dosage forms such as conventional tablets and capsules, microencapsulated products and fast disintegrating formulations. In addition, the company will also present its active pharmaceutical ingredients Omyapure® and Omya-Cal®, natural calcium carbonates for dietary supplements, antacids and osteoporosis treatments.
Omyapharm 500-OG is a fine powder consisting of calcium carbonate and tribasic calcium phosphate. It is suitable for wet and dry granulation as well as for hot-melt extrusion. Omyapharm 500-DG OG, meanwhile, is the granulated form of Omyapharm 500-OG and contains a superdisintegrant. Thanks to its special granulation, Omyapharm 500-DG OG offers improved flowability and can be directly compressed into tablets.
Omyapharm 500-DG OG has special importance when it comes to orally dispersible tablets (ODTs) and granules (ODGs). Its high porosity and specific surface properties enable fast disintegration and excellent compactibility that results in harder tablets at low compression forces. Tablets formulated with the functionalized calcium carbonate can be filled in conventional packaging because of their mechanical strength, thus reducing costs and difficulties during the conditioning process. ODTs manufactured from this excipient disintegrate in less than ten seconds. At Omya’s booth, CPhI visitors will be able to see flavored ODT samples and experience their fast disintegration properties first hand.
Omya will also showcase its natural calcium carbonates Omyapure and Omya-Cal. Natural calcium carbonate is a high purity calcium source with 40 percent bioavailable calcium. This makes it a valuable ingredient for calcium supplementation – for instance, to treat conditions such as osteoporosis – and for antacid formulations to neutralise stomach acid.
Thanks to their comprehensive formulation know-how, the company’s experts are able to develop tailor-made formulations in response to specific customer needs.